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Those included: lysine methylations on the C-terminus of the sequence or detected in peptides with acidic residues (doable artifacts of methyl esterification of the carboxylic group) and peptides with deamidation on the C-terminal arginine (tryptic cleavage after a deamidated residue have been lately proven as a highly unlikely event 41 ).
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PR-Set7-mediated monomethylation of histone H4 lysine 20 at particular genomic regions induces transcriptional repression.
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There are a number of different ways to administer the Lysine.